Concepedia

Alan C. Cheng

AC

Statistics

Publications

49

Citations

3.2K

H-Index

30

Active since

2003

Affiliations

Amgen (United States)(Current)

Merck & Co., Inc., Rahway, NJ, USA (United States)

Pfizer (United States)

Novartis (Switzerland)

University of California, San Francisco

Alan C. Cheng is an author at Amgen (United States) specializing in drug discovery, medicinal chemistry, and pharmacology.

Publications per year

2003–2024

49

Publications

49

Structure-based maximal affinity model predicts small-molecule druggability

Alan C. Cheng, Ryan G. Coleman, Kathleen T Smyth et al. · Nature Biotechnology · 2007 · 691 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies

Sean Caenepeel, Sean P. Brown, Brian Belmontes et al. · Cancer Discovery · 2018 · 419 citations · Full text

Medicine, Oncology, Pharmacology +14

Improvement in ADMET Prediction with Multitask Deep Featurization

Evan N. Feinberg, Elizabeth Joshi, Vijay S. Pande et al. · Journal of Medicinal Chemistry · 2020 · 198 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Recognition of Nucleic Acid Bases and Base-pairs by Hydrogen Bonding to Amino Acid Side-chains

Alan C. Cheng, William W. Chen, Cynthia N. Fuhrmann et al. · Journal of Molecular Biology · 2003 · 145 citations

Life Sciences, Biochemistry, Molecular Biology +16

Structure of the Catalytic Domain of Human Polo-like Kinase 1<sup>,</sup>

Michael Kothe, Darcy Kohls, Simon Low et al. · Biochemistry · 2007 · 123 citations

Life Sciences, Molecular Biology, Oncology +13

1–5 of 49