CSF1R signaling is a regulator of pathogenesis in progressive MS

Nellwyn Hagan, John L. Kane, Deepak Grover, +16

Cell Death and Disease

Research Article: Selectivity‐determining Residues in Plk1

Michael Kothe, Darcy Kohls, Simon Low, +5

Chemical Biology & Drug Design

Bi 2536Residue (Chemistry)Signaling PathwayMedicineReceptor Tyrosine Kinase +12

Structure of the Catalytic Domain of Human Polo-like Kinase 1^,

Michael Kothe, Darcy Kohls, Simon Low, +12

Biochemistry

Catalytic DomainMolecular BiologyChemical BiologyTumor BiologySignaling Pathway +17

Role of p97 AAA-ATPase in the Retrotranslocation of the Cholera Toxin A1 Chain, a Non-ubiquitinated Substrate

Michael Kothe, Yihong Ye, Jessica Wagner, +4

Journal of Biological Chemistry

Molecular BiologyCytoskeletonP97 Aaa-atpaseSecretory PathwayA1 Chain +16

Structural Determinants for Inhibitor Specificity and Selectivity in PDE2A Using the Wheat Germ in Vitro Translation System

André Iffland, Darcy Kohls, Simon Low, +7

Biochemistry

Identification of Allosteric PIF‐Pocket Ligands for PDK1 using NMR‐Based Fragment Screening and ¹H‐¹⁵N TROSY Experiments

Brian J. Stockman, Michael Kothe, Darcy Kohls, +9

Chemical Biology & Drug Design

Examination of poly(butadiene epoxide)-coatings on inorganic surfaces

Michael Kothe, Martin Müller, Frank Simon, +3

Colloids and Surfaces A Physicochemical and Engineering Aspects

Materials ScienceChemical EngineeringEngineeringSurface ScienceButadiene Epoxide +3

Beyond the MEK-pocket: Can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

Haile Tecle, Jianxing Shao, Yanhong Li, +10

Bioorganic & Medicinal Chemistry Letters

Mek-pocket ExistMedicineReceptor Tyrosine KinasePharmacologyCell Biology +1

On-Surface Synthesis and Characterization of an Iron Corrole

Martin Schmid, Malte Zugermeier, Jan Herritsch, +8

The Journal of Physical Chemistry C

EngineeringCoordinated Metal IonChemistryCorrosion InhibitionChemical Engineering +15

Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma

Haibo Liu, Deqiang Niu, Robert Tjin Tham Sjin, +19

ACS Medicinal Chemistry Letters