Jack Dempsey

The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade

David Schaer, Richard P. Beckmann, Jack Dempsey et al. · Cell Reports · 2018 · 460 citations · Full text

Medicine, Immunology, Pharmacology +17

Central amygdala ERK signaling pathway is critical to incubation of cocaine craving

Lin Lü, Bruce T. Hope, Jack Dempsey et al. · Nature Neuroscience · 2005 · 445 citations

Medicine, Neurobiology, Neuroscience +12

A Single Infusion of Brain-Derived Neurotrophic Factor into the Ventral Tegmental Area Induces Long-Lasting Potentiation of Cocaine Seeking after Withdrawal

Lin Lü, Jack Dempsey, Shirley Y. Liu et al. · Journal of Neuroscience · 2004 · 284 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib

Xueqian Gong, Lacey M. Litchfield, Yue Webster et al. · Cancer Cell · 2017 · 236 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms

Constance King, H. Bruce Diaz, Samuel McNeely et al. · Molecular Cancer Therapeutics · 2015 · 189 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17