Central amygdala ERK signaling pathway is critical to incubation of cocaine craving

Lin Lü, Bruce T. Hope, Jack Dempsey, +3

Nature Neuroscience

NeuropsychologyCentral Amygdala ErkCocaine CravingBehavioral AddictionAffective Neuroscience +14

The CDK4/6 Inhibitor Abemaciclib Induces a T Cell Inflamed Tumor Microenvironment and Enhances the Efficacy of PD-L1 Checkpoint Blockade

David Schaer, Richard P. Beckmann, Jack Dempsey, +19

Cell Reports

A Single Infusion of Brain-Derived Neurotrophic Factor into the Ventral Tegmental Area Induces Long-Lasting Potentiation of Cocaine Seeking after Withdrawal

Lin Lü, Jack Dempsey, Shirley Y. Liu, +2

Journal of Neuroscience

NeuropsychologyBehavioral AddictionSingle InfusionNeurotransmitterCocaine +20

Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib

Xueqian Gong, Lacey M. Litchfield, Yue Webster, +27

Cancer Cell

Cdk6 Inhibitor AbemaciclibSignal TransductionSignaling PathwayGenomic AberrationsCell Regulation +8

LY2606368 Causes Replication Catastrophe and Antitumor Effects through CHK1-Dependent Mechanisms

Constance King, H. Bruce Diaz, Samuel McNeely, +6

Molecular Cancer Therapeutics

Dna DamageMolecular BiologyCell DeathCell CycleTumor Biology +16

Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months

Lin Lü, Jeffrey W. Grimm, Jack Dempsey, +1

Psychopharmacology

Substance AbuseBehavioral SciencesSubstance UseBehavioral NeuroscienceAddiction +10

Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase

Hui Yang, Teresa F. Burke, Jack Dempsey, +5

FEBS Letters

Molecular BiologyCell DeathCytoskeletonAurora BCell Cycle +15

Using neural networks to diagnose cancer

Philip S. Maclin, Jack Dempsey, J.W. Brooks, +1

Journal of Medical Systems

EngineeringCancer DetectionMedical Image ComputingDigital PathologyDiagnosis +7

Thrombopoietin and Its Receptor, c-mpl, Are Constitutively Expressed by Mouse Liver Endothelial Cells: Evidence of Thrombopoietin as a Growth Factor for Liver Endothelial Cells

José E. Cardier, Jack Dempsey

Blood

Synthesis, Structure−Activity Relationship, and Biological Studies of Indolocarbazoles as Potent Cyclin D1-CDK4 Inhibitors

Guoxin Zhu, Scott E. Conner, Xun Zhou, +14

Journal of Medicinal Chemistry

Medicinal ChemistryBioorganic ChemistryHeterocyclicBiochemistryStructure−activity Relationship +12