Yue Webster

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

Sheng-Bin Peng, James R. Henry, Michael D. Kaufman et al. · Cancer Cell · 2015 · 309 citations · Full text

Medicine, Cancer Biology, Oncology +16

Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib

Xueqian Gong, Lacey M. Litchfield, Yue Webster et al. · Cancer Cell · 2017 · 236 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the <i>RB1</i> Tumor Suppressor Gene

Xueqian Gong, Jian Du, Stephen H. Parsons et al. · Cancer Discovery · 2018 · 233 citations

Life Sciences, Oncology, Pharmacology +17

Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity

Jeffrey J. Sutherland, Yue Webster, Jeffrey A. Willy et al. · The Pharmacogenomics Journal · 2017 · 100 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Abemaciclib Is Active in Preclinical Models of Ewing Sarcoma via Multipronged Regulation of Cell Cycle, DNA Methylation, and Interferon Pathway Signaling

Michele Dowless, Caitlin D. Lowery, Terry J. Shackleford et al. · Clinical Cancer Research · 2018 · 69 citations

Medicine, Oncology, Pharmacology +17