James R. Henry

Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

Sheng-Bin Peng, James R. Henry, Michael D. Kaufman et al. · Cancer Cell · 2015 · 309 citations · Full text

Medicine, Cancer Biology, Oncology +16

Imidazopyrimidines, potent inhibitors of p38 MAP kinase

Kenneth C. Rupert, James R. Henry, John H. Dodd et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 252 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the <i>RB1</i> Tumor Suppressor Gene

Xueqian Gong, Jian Du, Stephen H. Parsons et al. · Cancer Discovery · 2018 · 233 citations

Life Sciences, Oncology, Pharmacology +17

Mitsunobu reactions of n-alkyl and n-acyl sulfonamides-an efficient route to protected amines

James R. Henry, Lawrence R. Marcin, Matthias C. McIntosh et al. · Tetrahedron Letters · 1989 · 206 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7

Reactivation of Mitogen-activated Protein Kinase (MAPK) Pathway by FGF Receptor 3 (FGFR3)/Ras Mediates Resistance to Vemurafenib in Human B-RAF V600E Mutant Melanoma

Vipin Yadav, Xiaoyi Zhang, Jiangang Liu et al. · Journal of Biological Chemistry · 2012 · 204 citations · Full text

Medicine, Oncology, Pharmacology +15