Annette Bak

Physicochemical Properties of Pharmaceutical Co-Crystals: A Case Study of Ten AMG 517 Co-Crystals

Mary K. Stanton, Annette Bak · Crystal Growth & Design · 2008 · 232 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

The Co‐Crystal Approach to Improve the Exposure of a Water‐Insoluble Compound: AMG 517 Sorbic Acid Co‐Crystal Characterization and Pharmacokinetics

Annette Bak, Anu Gore, Evelyn Yanez et al. · Journal of Pharmaceutical Sciences · 2008 · 218 citations

Pharmacy, Chemistry, Pharmacokinetics +11

Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale

Prasath Paramasivam, Christian Franke, Martin Stöter et al. · The Journal of Cell Biology · 2021 · 192 citations · Full text

Pharmacy, Molecular Biology, Pharmaceutics +17

Repeated Administration of Vanilloid Receptor TRPV1 Antagonists Attenuates Hyperthermia Elicited by TRPV1 Blockade

Narender R. Gavva, Anthony W. Bannon, David N. Hovland et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 174 citations

Medicine, Medicinal Chemistry, Pharmacology +15

Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-<i>N</i>-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1<i>H</i>-pyrazole-4-carboxamide (AMG 458)

Longbin Liu, Aaron Siegmund, Ning Xi et al. · Journal of Medicinal Chemistry · 2008 · 95 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14