The Co‐Crystal Approach to Improve the Exposure of a Water‐Insoluble Compound: AMG 517 Sorbic Acid Co‐Crystal Characterization and Pharmacokinetics

Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?

�rn Almarsson, Michael J. Zaworotko · Chemical Communications · 2004 · 1.1K citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Systematic analysis of structural data as a research technique in organic chemistry

Frank H. Allen, Olga Kennard, Robin Taylor · Accounts of Chemical Research · 1983 · 1K citations

Natural Sciences, Chemistry, Analytical Chemistry +12

Superstructural diversity in two dimensions: crystal engineering of laminated solids

Michael J. Zaworotko · Chemical Communications · 2001 · 765 citations

Natural Sciences, Chemistry, Materials Science +17

Use of a Glutaric Acid Cocrystal to Improve Oral Bioavailability of a Low Solubility API

Daniel P. McNamara, S.L. Childs, Jennifer Giordano et al. · Pharmaceutical Research · 2006 · 687 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +16

Crystal Engineering of Novel Cocrystals of a Triazole Drug with 1,4-Dicarboxylic Acids

Julius F. Remenar, Sherry L. Morissette, Matthew L. Peterson et al. · Journal of the American Chemical Society · 2003 · 681 citations

Pharmacy, Chemistry, Pharmacology +17