Concepedia

Co-crystal Formation

Co-Crystal Formation is a solid-state crystallization process in which two or more different molecular or ionic compounds, typically an active pharmaceutical ingredient and a co-former, reversibly associate in a stoichiometric ratio through non-covalent interactions to form a single, distinct crystalline phase with enhanced solubility and physicochemical properties.

1.3K

Publications

65.5K

Citations

4.1K

Authors

1.2K

Institutions

Publications per year

2017–2026

518

Parents

Publications

1.3K

Pharmaceutical Cocrystals and Their Physicochemical Properties

N. Schultheiss, Ann Newman · Crystal Growth & Design · 2009 · 1.5K citations · Full text

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Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?

�rn Almarsson, Michael J. Zaworotko · Chemical Communications · 2004 · 1.1K citations

, , +17

Recent Advances in Understanding the Mechanism of Cocrystal Formation via Grinding

Tomislav Friščić, William Jones · Crystal Growth & Design · 2009 · 732 citations

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Crystal Engineering Approach To Forming Cocrystals of Amine Hydrochlorides with Organic Acids. Molecular Complexes of Fluoxetine Hydrochloride with Benzoic, Succinic, and Fumaric Acids

S.L. Childs, Leonard J. Chyall, J.T. Dunlap et al. · Journal of the American Chemical Society · 2004 · 630 citations · Full text

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Hansen solubility parameter as a tool to predict cocrystal formation

Mohammad Amin Mohammad, Amjad Alhalaweh, Sitaram P. Velaga · International Journal of Pharmaceutics · 2011 · 519 citations

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Authors

4.1K

  1. WJ
    William Jones

    University of Cambridge, United Kingdom

    29 publications · 4K citations

    26

    h-index

  2. DB
    Dario Braga

    University of Bologna, Italy

    35 publications · 1.9K citations

    25

    h-index

  3. FG
    Fabrizia Grepioni

    University of Bologna, Italy

    35 publications · 1.9K citations

    25

    h-index

  4. AN
    Ashwini Nangia

    University of Hyderabad, India

    25 publications · 2.2K citations

    23

    h-index

  5. CB
    Christer B. Aakeröy

    Kansas State University, United States

    25 publications · 1.6K citations

    22

    h-index

1–5 of 4.1K

Institutions

1.2K

  1. University of Hyderabad

    Hyderabad, India

    28 h-index

    84 publications

    7.7K citations

  2. University of Bologna

    Bologna, Italy

    26 h-index

    135 publications

    7.2K citations

  3. University of Cambridge

    Cambridge, United Kingdom

    25 h-index

    91 publications

    9K citations

  4. Indian Institute of Science Bangalore

    Bengaluru, India

    24 h-index

    77 publications

    6K citations

  5. Kansas State University

    Manhattan, United States

    23 h-index

    79 publications

    5.2K citations

  6. Chinese Academy of Sciences

    Beijing, China

    20 h-index

    89 publications

    4.1K citations

  7. University of Bradford

    Bradford, United Kingdom

    17 h-index

    78 publications

    4.2K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    16 h-index

    88 publications

    3.3K citations

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Venues

  1. Crystal Growth & Design

    283 publications · 17.7K citations

    71

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  2. CrystEngComm

    231 publications · 11.7K citations

    57

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  3. Chemical Communications

    ChemComm · 59 publications · 5.6K citations

    36

    h-index

  4. Journal of Pharmaceutical Sciences

    32 publications · 2.3K citations

    27

    h-index

  5. Journal of Molecular Structure

    54 publications · 1.4K citations

    23

    h-index

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