Karina Romero

Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

Marc Payton, Tammy L. Bush, Grace Chung et al. · Cancer Research · 2010 · 118 citations · Full text

Cell Death, Novel Potent, Cancer Biology +18

Pyridyl-pyrimidine benzimidazole derivatives as potent, selective, and orally bioavailable inhibitors of Tie-2 kinase

Victor J. Cee, Alan C. Cheng, Karina Romero et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 64 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Tie-2 Kinase +12

The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Richard T. Lewis, Christiane Bode, Deborah M. Choquette et al. · Journal of Medicinal Chemistry · 2012 · 43 citations · Full text

Pharmaceutical Chemistry, Anaplastic Lymphoma Kinase, Tumor Biology +16

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Victor J. Cee, Laurie B. Schenkel, Brian L. Hodous et al. · Journal of Medicinal Chemistry · 2010 · 37 citations · Full text

Pharmaceutical Science, Chemoprevention Strategy, Kinase Inhibitors +16

Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors

Emily A. Peterson, Alessandro A. Boezio, Paul S. Andrews et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 36 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +13