Deborah M. Choquette

Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Brian K. Albrecht, Jean-Christophe Harmange, David Bauer et al. · Journal of Medicinal Chemistry · 2008 · 139 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

Naphthamides as Novel and Potent Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitors: Design, Synthesis, and Evaluation

Jean-Christophe Harmange, Matthew M. Weiss, Julie Germain et al. · Journal of Medicinal Chemistry · 2008 · 70 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Discovery and optimization of potent and selective triazolopyridazine series of c-Met inhibitors

Alessandro A. Boezio, Loren Berry, Brian K. Albrecht et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 56 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +13

<i>In Vitro</i> and <i>In Vivo</i> Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models

Paul E. Hughes, Karen Rex, Sean Caenepeel et al. · Molecular Cancer Therapeutics · 2016 · 55 citations

Medicine, Oncology, Pharmacology +16

The Discovery and Optimization of a Novel Class of Potent, Selective, and Orally Bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with Potential Utility for the Treatment of Cancer

Richard T. Lewis, Christiane Bode, Deborah M. Choquette et al. · Journal of Medicinal Chemistry · 2012 · 45 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15