Paul E. Hughes

Integrin activation controls metastasis in human breast cancer

Brunhilde Felding‐Habermann, Timothy E. O’Toole, Jeffrey W. Smith et al. · Proceedings of the National Academy of Sciences · 2001 · 580 citations

Life Sciences, Cell Biology, Oncology +16

Breaking the Integrin Hinge

Paul E. Hughes, Federico Díaz‐González, Lilley Leong et al. · Journal of Biological Chemistry · 1996 · 562 citations · Full text

Life Sciences, Surgery, Mechanobiology +4

Suppression of Integrin Activation: A Novel Function of a Ras/Raf-Initiated MAP Kinase Pathway

Paul E. Hughes, Mark W. Renshaw, Martin Pfaff et al. · Cell · 1997 · 495 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies

Sean Caenepeel, Sean P. Brown, Brian Belmontes et al. · Cancer Discovery · 2018 · 419 citations · Full text

Medicine, Oncology, Pharmacology +14

Complementation of dominant suppression implicates CD98 in integrin activation

Csilla A. Fenczik, Tariq Sethi, Joe W. Ramos et al. · Nature · 1997 · 289 citations

Life Sciences, Cell Biology, Molecular Biology +11