Karen Rex

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

Jude Canon, Karen Rex, Anne Y. Saiki et al. · Nature · 2019 · 2.2K citations

Cancer Immunosurveillance, Clinical Kras, Immunology +5

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 677 citations · Full text

Drug Target, Solid Tumors, Molecular Biology +20

Keratinocyte growth factor protects mice from chemotherapy and radiation-induced gastrointestinal injury and mortality.

Catherine L. Farrell, J. V. Bready, Karen Rex et al. · PubMed · 1998 · 362 citations

Radiation Effect, Immunology, Immune Regulation +19

Fully Human Monoclonal Antibodies to Hepatocyte Growth Factor with Therapeutic Potential against Hepatocyte Growth Factor/c-Met–Dependent Human Tumors

Teresa L. Burgess, Angela Coxon, Susanne Meyer et al. · Cancer Research · 2006 · 252 citations

Influences of neurotrophins on mammalian motoneurons <i>in vivo</i>

Yan Qiao, Jeffrey L. Elliott, Christine R. Matheson et al. · Journal of Neurobiology · 1993 · 198 citations

Synaptic Transmission, Spinal Motoneurons, Retrograde Transport +19