Alessandro A. Boezio

Asymmetric, Catalytic Synthesis of α-Chiral Amines Using a Novel Bis(phosphine) Monoxide Chiral Ligand

Alessandro A. Boezio, Julien Pytkowicz, Alexandre Côté et al. · Journal of the American Chemical Society · 2003 · 158 citations

Natural Sciences, Chemistry, Catalysis +13

Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Brian K. Albrecht, Jean-Christophe Harmange, David Bauer et al. · Journal of Medicinal Chemistry · 2008 · 139 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

Catalytic Enantioselective Addition of Dialkylzinc to <i>N</i>-Diphenylphosphinoylimines. A Practical Synthesis of α-Chiral Amines

Alessandro A. Boezio, André B. Charette · Journal of the American Chemical Society · 2003 · 97 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5

Catalytic asymmetric addition of diorganozinc reagents to <i>N</i> -phosphinoylalkylimines

Alexandre Côté, Alessandro A. Boezio, André B. Charette · Proceedings of the National Academy of Sciences · 2004 · 96 citations · Full text

Natural Sciences, Chemistry, Catalysis +6

Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia

Andreas Varkaris, Ermira Pazolli, Hakan Günaydin et al. · Cancer Discovery · 2023 · 90 citations · Full text

Life Sciences, Medicinal Chemistry, Oncology +17