Alexandre Côté

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials

Brian K. Albrecht, Victor Gehling, Michael C. Hewitt et al. · Journal of Medicinal Chemistry · 2016 · 214 citations · Full text

Immunology, Pharmacotherapy, Tumor Biology +22

Disrupting Acetyl-Lysine Recognition: Progress in the Development of Bromodomain Inhibitors

F. Anthony Romero, Alexander M. Taylor, Terry D. Crawford et al. · Journal of Medicinal Chemistry · 2015 · 188 citations · Full text

Drug Target, Pharmacotherapy, Pharmaceutical Chemistry +18

Asymmetric, Catalytic Synthesis of α-Chiral Amines Using a Novel Bis(phosphine) Monoxide Chiral Ligand

Alessandro A. Boezio, Julien Pytkowicz, Alexandre Côté et al. · Journal of the American Chemical Society · 2003 · 157 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +16

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

Terry D. Crawford, Vickie Tsui, E. Megan Flynn et al. · Journal of Medicinal Chemistry · 2016 · 117 citations · Full text

Molecular Biology, Chemical Biology, Pharmaceutical Chemistry +17

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

Alexander M. Taylor, Alexandre Côté, Michael C. Hewitt et al. · ACS Medicinal Chemistry Letters · 2016 · 111 citations · Full text

Drug Target, Chemical Biology, Cancer Biology +16