S.F. Bellon

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

Maia Vinogradova, Victor Gehling, Amy Gustafson et al. · Nature Chemical Biology · 2016 · 343 citations · Full text

Drug-tolerant Cancer Cells, Medicine, Anti-cancer Agent +7

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 222 citations · Full text

Bioorganic Chemistry, Antibacterial Activity, Molecular Biology +23

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-0610) of the Bromodomain and Extra-Terminal (BET) Family as a Candidate for Human Clinical Trials

Brian K. Albrecht, Victor Gehling, Michael C. Hewitt et al. · Journal of Medicinal Chemistry · 2016 · 214 citations · Full text

Immunology, Pharmacotherapy, Tumor Biology +22

A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications

E. Megan Flynn, Oscar W. Huang, Florence Poy et al. · Structure · 2015 · 209 citations · Full text

Chromatin, Chromatin Remodeling, Epigenetic Change +6

The structure of phosphorylated P38γ is monomeric and reveals a conserved activation-loop conformation

S.F. Bellon, Matthew J. Fitzgibbon, Ted Fox et al. · Structure · 1999 · 131 citations · Full text

Conserved Activation-loop Conformation, Protein Function, Signal Transduction +8