Anne‐Laure Grillot

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 225 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase

Steven Ronkin, Michael C. Badia, S.F. Bellon et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 107 citations

Pharmacy, Chemical Biology, Medicinal Chemistry +9

Dual Targeting of GyrB and ParE by a Novel Aminobenzimidazole Class of Antibacterial Compounds

Trudy H. Grossman, Douglas J. Bartels, Steve Mullin et al. · Antimicrobial Agents and Chemotherapy · 2006 · 90 citations · Full text

Life Sciences, Microbiology, Pharmacology +15

In Vitro Characterization of the Antibacterial Spectrum of Novel Bacterial Type II Topoisomerase Inhibitors of the Aminobenzimidazole Class

Nagraj Mani, Christian H. Gross, Jonathan D. Parsons et al. · Antimicrobial Agents and Chemotherapy · 2006 · 82 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability

Anne‐Laure Grillot, Arnaud LeTiran, Dean Shannon et al. · Journal of Medicinal Chemistry · 2014 · 82 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16