Concepedia

Anne‐Laure Grillot

AG

Statistics

Publications

11

Citations

742

H-Index

11

Active since

1995

Affiliations

Vertex Pharmaceuticals (United States)(Current)

Vertex Pharmaceuticals (Canada)

Hartford Hospital

Anne‐Laure Grillot is an author at Vertex Pharmaceuticals (United States) specializing in medicinal chemistry, drug discovery, and pharmacy.

Publications per year

1995–2015

11

Publications

11

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 225 citations · Full text

, , +16

Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase

Steven Ronkin, Michael C. Badia, S.F. Bellon et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 107 citations

, , +9

Dual Targeting of GyrB and ParE by a Novel Aminobenzimidazole Class of Antibacterial Compounds

Trudy H. Grossman, Douglas J. Bartels, Steve Mullin et al. · Antimicrobial Agents and Chemotherapy · 2006 · 90 citations · Full text

, , +15

In Vitro Characterization of the Antibacterial Spectrum of Novel Bacterial Type II Topoisomerase Inhibitors of the Aminobenzimidazole Class

Nagraj Mani, Christian H. Gross, Jonathan D. Parsons et al. · Antimicrobial Agents and Chemotherapy · 2006 · 82 citations · Full text

, , +16

Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability

Anne‐Laure Grillot, Arnaud LeTiran, Dean Shannon et al. · Journal of Medicinal Chemistry · 2014 · 82 citations · Full text

, , +16

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