Jonathan D. Parsons

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 222 citations · Full text

Bioorganic Chemistry, Antibacterial Activity, Molecular Biology +23

Crystal Structures of <i>Escherichia coli</i> Topoisomerase IV ParE Subunit (24 and 43 Kilodaltons): a Single Residue Dictates Differences in Novobiocin Potency against Topoisomerase IV and DNA Gyrase

Steven F. Bellon, Jonathan D. Parsons, Yunyi Wei et al. · Antimicrobial Agents and Chemotherapy · 2004 · 156 citations · Full text

Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase

Steven Ronkin, Michael C. Badia, S.F. Bellon et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 104 citations

Antifungal Agent, Medicine, Bacterial Gyrase +9

Active-Site Residues of <i>Escherichia coli</i> DNA Gyrase Required in Coupling ATP Hydrolysis to DNA Supercoiling and Amino Acid Substitutions Leading to Novobiocin Resistance

Christian H. Gross, Jonathan D. Parsons, Trudy H. Grossman et al. · Antimicrobial Agents and Chemotherapy · 2003 · 91 citations · Full text

Dual Targeting of GyrB and ParE by a Novel Aminobenzimidazole Class of Antibacterial Compounds

Trudy H. Grossman, Douglas J. Bartels, Steve Mullin et al. · Antimicrobial Agents and Chemotherapy · 2006 · 90 citations · Full text

Combinatorial Chemistry, Bioorganic Chemistry, Escherichia Coli +21