Steven F. Bellon

DNA unwinding produced by site-specific intrastrand crosslinks of the antitumor drug cis-diamminedichloroplatinum(II)

Steven F. Bellon, Julia H. Coleman, S.J. Lippard · Biochemistry · 1991 · 292 citations

Medicine, Cancer Biology, Molecular Biology +6

The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity

Marc Jacobs, Koto Hayakawa, Lora Swenson et al. · Journal of Biological Chemistry · 2005 · 259 citations · Full text

Life Sciences, Biochemistry, Chemistry +14

Identification of (<i>R</i>)-<i>N</i>-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1<i>H</i>-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas

Rishi G. Vaswani, Victor Gehling, Les A. Dakin et al. · Journal of Medicinal Chemistry · 2016 · 220 citations · Full text

Medicine, Oncology, Pharmacology +16

Crystal Structures of <i>Escherichia coli</i> Topoisomerase IV ParE Subunit (24 and 43 Kilodaltons): a Single Residue Dictates Differences in Novobiocin Potency against Topoisomerase IV and DNA Gyrase

Steven F. Bellon, Jonathan D. Parsons, Yunyi Wei et al. · Antimicrobial Agents and Chemotherapy · 2004 · 157 citations · Full text

Life Sciences, Biology, Microbiology +13

Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3) 2 (N3-cytosine) Cl]+

Steven F. Bellon, Stephen J. Lippard · Biophysical Chemistry · 1990 · 147 citations

Life Sciences, Biology, Molecular Biology +8