Concepedia

Marc Jacobs

MJ

Statistics

Publications

52

Citations

3.6K

H-Index

29

Active since

1993

Affiliations

Vertex Pharmaceuticals (United States)(Current)

University of Auckland

Fraunhofer Institute for Algorithms and Scientific Computing

Yale University

University of Bonn

Marc Jacobs is an author at Vertex Pharmaceuticals (United States) specializing in drug discovery, medicinal chemistry, and pharmacy.

ORCID

Publications per year

1993–2024

52

Publications

52

Structure of an IκBα/NF-κB Complex

Marc Jacobs, Stephen C. Harrison · Cell · 1998 · 819 citations · Full text

, , +12

The Structure of Dimeric ROCK I Reveals the Mechanism for Ligand Selectivity

Marc Jacobs, Koto Hayakawa, Lora Swenson et al. · Journal of Biological Chemistry · 2005 · 259 citations · Full text

, , +14

Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

Michael P. Clark, Mark W. Ledeboer, Ioana Davies et al. · Journal of Medicinal Chemistry · 2014 · 211 citations · Full text

, , +17

Pim-1 Ligand-bound Structures Reveal the Mechanism of Serine/Threonine Kinase Inhibition by LY294002

Marc Jacobs, James Black, Olga Futer et al. · Journal of Biological Chemistry · 2005 · 189 citations · Full text

, , +9

Preclinical Activity of VX-787, a First-in-Class, Orally Bioavailable Inhibitor of the Influenza Virus Polymerase PB2 Subunit

Randal A. Byrn, Hamilton B. Bennett, Chris Bral et al. · Antimicrobial Agents and Chemotherapy · 2014 · 188 citations · Full text

, , +17

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