Ioana Davies

Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

Michael P. Clark, Mark W. Ledeboer, Ioana Davies et al. · Journal of Medicinal Chemistry · 2014 · 207 citations · Full text

Influenza Pb2, Medicinal Chemistry, Medicine +13

A randomised controlled trial and cost analysis of problem-solving treatment for emotional disorders given by community nurses in primary care

Laurence Mynors‐Wallis, Ioana Davies, Alastair Gray et al. · The British Journal of Psychiatry · 1997 · 173 citations

Novel 2-Substituted 7-Azaindole and 7-Azaindazole Analogues as Potential Antiviral Agents for the Treatment of Influenza

Upul K. Bandarage, Michael P. Clark, Emanuele Perola et al. · ACS Medicinal Chemistry Letters · 2017 · 48 citations · Full text

Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors

Michael J. Boyd, Upul K. Bandarage, Hamilton B. Bennett et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 31 citations · Full text

Drug Candidate Vx-787, Medicinal Chemistry, Biochemistry +11

Development of a Scalable Synthesis of an Azaindolyl-Pyrimidine Inhibitor of Influenza Virus Replication

Jianglin Liang, John E. Cochran, Warren A. Dorsch et al. · Organic Process Research & Development · 2016 · 20 citations

Viral Replication, Synthetic Virology, Molecular Biology +19