Concepedia

Emanuele Perola

EP

Statistics

Publications

33

Citations

3.5K

H-Index

26

Active since

1995

Affiliations

Vertex Pharmaceuticals (United States)(Current)

Mayo Clinic

Istituto di Metodologie Chimiche

Blueprint Medicines (United States)

International Centre for Genetic Engineering and Biotechnology

Emanuele Perola is an author at Vertex Pharmaceuticals (United States) specializing in medicinal chemistry, drug discovery, and pharmacology.

Publications per year

1995–2022

33

Publications

33

Conformational Analysis of Drug-Like Molecules Bound to Proteins:  An Extensive Study of Ligand Reorganization upon Binding

Emanuele Perola, Paul S. Charifson · Journal of Medicinal Chemistry · 2004 · 448 citations

, , +15

A detailed comparison of current docking and scoring methods on systems of pharmaceutical relevance

Emanuele Perola, W. Patrick Walters, Paul S. Charifson · Proteins Structure Function and Bioinformatics · 2004 · 448 citations

, , +17

Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment

Brian C. VanderVen, Ruth J. Fahey, Wonsik Lee et al. · PLoS Pathogens · 2015 · 274 citations · Full text

, , +16

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 225 citations · Full text

, , +16

Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

Michael P. Clark, Mark W. Ledeboer, Ioana Davies et al. · Journal of Medicinal Chemistry · 2014 · 211 citations · Full text

, , +17

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