Trudy H. Grossman

Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

Michelle R. Rondon, Paul R. August, Alan D. Bettermann et al. · Applied and Environmental Microbiology · 2000 · 1.2K citations

Life Sciences, Biology, Microbiology +17

Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

Shenping Liu, Trudy H. Grossman, Tim Ocain et al. · Structure · 2000 · 340 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +12

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 225 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Spontaneous cAMP-dependent derepression of gene expression in stationary phase plays a role in recombinant expression instability

Trudy H. Grossman, Ernest S. Kawasaki, Sandhya R. Punreddy et al. · Gene · 1998 · 210 citations

Life Sciences, Genetics, Molecular Biology +13

Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline Antibiotic

Trudy H. Grossman, Agata L. Starosta, Corey Fyfe et al. · Antimicrobial Agents and Chemotherapy · 2012 · 163 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17