Paul R. August

Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

Michelle R. Rondon, Paul R. August, Alan D. Bettermann et al. · Applied and Environmental Microbiology · 2000 · 1.2K citations · Full text

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Yingxiao Shi, Shao‐Yu Lin, Kim A. Staats et al. · Nature Medicine · 2018 · 570 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Neuroscience +11

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699

Paul R. August, Li Tang, Yeo Joon Yoon et al. · Chemistry & Biology · 1998 · 348 citations · Full text

Biosynthesis, Engineering, Biotransformation +10

Recombinant Environmental Libraries Provide Access to Microbial Diversity for Drug Discovery from Natural Products

Sophie Courtois, Carmela Cappellano, María M. Ball et al. · Applied and Environmental Microbiology · 2003 · 348 citations · Full text

Expression and isolation of antimicrobial small molecules from soil DNA libraries.

I A MacNeil, Choi Lai Tiong, C Minor et al. · PubMed · 2001 · 213 citations

Engineering, Soil Dna Libraries, Molecular Biology +16