Yingxiao Shi

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

Yingxiao Shi, Shao‐Yu Lin, Kim A. Staats et al. · Nature Medicine · 2018 · 570 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Neuroscience +11

Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death

Xinmei Wen, Wenzhi Tan, Thomas Westergard et al. · Neuron · 2014 · 545 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Medicine +8

CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity

Nicholas J. Kramer, Michael S. Haney, David W. Morgens et al. · Nature Genetics · 2018 · 235 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Synaptic Signaling +12

RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats

Shizuka Yamada, Tania F. Gendron, Teresa Niccoli et al. · Nature Neuroscience · 2019 · 108 citations

Neurodegenerative Diseases, Natural Sciences, Genetics +9

Notch inhibition allows oncogene-independent generation of iPS cells

Justin K. Ichida, Julia TCW, Luis A. Williams et al. · Nature Chemical Biology · 2014 · 72 citations · Full text

Developmental Biology, Signal Transduction, Cell Regulation +6