Nicholas J. Kramer

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

Ana Jovičić, Jérôme Mertens, Steven Boeynaems et al. · Nature Neuroscience · 2015 · 616 citations · Full text

Nucleocytoplasmic Transport Defects, Amyotrophic Lateral Sclerosis, Biochemistry +4

CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity

Nicholas J. Kramer, Michael S. Haney, David W. Morgens et al. · Nature Genetics · 2018 · 235 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Synaptic Signaling +12

LRRK2 modifies α-syn pathology and spread in mouse models and human neurons

Gregor Bieri, Michel Brahic, Luc Bousset et al. · Acta Neuropathologica · 2019 · 189 citations · Full text

Parkinson’s Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein

Nripesh Dhungel, Simona Eleuteri, Ling-bo Li et al. · Neuron · 2014 · 168 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Genetics +8

Spt4 selectively regulates the expression of <i>C9orf72</i> sense and antisense mutant transcripts

Nicholas J. Kramer, Yari Carlomagno, Yong‐Jie Zhang et al. · Science · 2016 · 126 citations · Full text

Rna Splicing, Molecular Biology, Expanded Ggcccc Repeats +19