Yong‐Jie Zhang

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

Yong‐Jie Zhang, Ya-Fei Xu, Casey Cook et al. · Proceedings of the National Academy of Sciences · 2009 · 606 citations · Full text

Apoptosis, Cell Death, Molecular Biology +18

Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS

Tania F. Gendron, Kevin F. Bieniek, Yong‐Jie Zhang et al. · Acta Neuropathologica · 2013 · 575 citations · Full text

Chromatin, Neurodegenerative Diseases, Rna Processing +14

TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

Ching-Chieh Chou, Yi Zhang, Mfon Umoh et al. · Nature Neuroscience · 2018 · 568 citations · Full text

Sporadic Als, Molecular Biology, Neurochemical Biomarkers +17

Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice

Ya-Fei Xu, Tania F. Gendron, Yong‐Jie Zhang et al. · Journal of Neuroscience · 2010 · 560 citations · Full text

Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis

Nicola J. Rutherford, Yong‐Jie Zhang, Matt Baker et al. · PLoS Genetics · 2008 · 458 citations · Full text

Neurodegenerative Diseases, Ubiquitin Inclusions, Amyotrophic Lateral Sclerosis +13