Jérôme Mertens

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

Jérôme Mertens, Apuã C.M. Paquola, Manching Ku et al. · Cell stem cell · 2015 · 717 citations · Full text

Lifespan Extension, Neurodegenerative Diseases, Molecular Neuroscience +10

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

Xinde Zheng, Leah Boyer, Mingji Jin et al. · eLife · 2016 · 643 citations · Full text

Neuronal Differentiation, Mitochondrial Biology, Metabolic Remodeling +19

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS

Ana Jovičić, Jérôme Mertens, Steven Boeynaems et al. · Nature Neuroscience · 2015 · 616 citations · Full text

Nucleocytoplasmic Transport Defects, Amyotrophic Lateral Sclerosis, Biochemistry +4

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

Bahareh Eftekharzadeh, J. Gavin Daigle, Larisa E. Kapinos et al. · Neuron · 2018 · 423 citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Neuroscience +8

Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro

Cédric Bardy, Mark van den Hurk, Tameji Eames et al. · Proceedings of the National Academy of Sciences · 2015 · 408 citations · Full text