Yunyi Wei

Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

Robert B. Perni, Susan J. Almquist, Randal A. Byrn et al. · Antimicrobial Agents and Chemotherapy · 2006 · 382 citations · Full text

In Vitro Resistance Studies of Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

Chao Lin, Kai Lin, Yu-Ping Luong et al. · Journal of Biological Chemistry · 2004 · 289 citations · Full text

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 222 citations · Full text

Bioorganic Chemistry, Antibacterial Activity, Molecular Biology +23

In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061

Chao Lin, Cynthia A. Gates, B. Govinda Rao et al. · Journal of Biological Chemistry · 2005 · 216 citations · Full text

Viral Hepatitis, Ns3.4a Serine Protease, Natural Sciences +14

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity

Yunyi Wei, Ted Fox, Steve P. Chambers et al. · Chemistry & Biology · 2000 · 197 citations · Full text

Protein Function, Signal Transduction, Biochemistry +9