Dean Shannon - Concepedia

Author

Dean Shannon

Vertex Pharmaceuticals (United States)

Also Known As

Dean E Shannon, Dean E. Shannon, Dean Shannon, Shannon, D.E., Shannon, Dean

Publications

478

Citations

H-Index

Concepts

All Affiliations

Vertex Pharmaceuticals (United States)Vertex Pharmaceuticals (Canada)Hartford Hospital

About

Dean Shannon is an author at Vertex Pharmaceuticals (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	410
2	Natural Sciences	3	3	323
3	Biochemistry	2	2	101
4	Chemical Biology	2	2	243
5	Allergy	1	1	87

Dean Shannon

Publications

471

Citations

H-Index

Page 1

	Year	Citations
Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman, Journal of Medicinal Chemistry Bioorganic ChemistryAntibacterial ActivityMolecular BiologyChemical BiologyPharmaceutical Chemistry	2008	222
Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases Luc J. Farmer, Mark W. Ledeboer, Thomas Hoock, Journal of Medicinal Chemistry ImmunologyImmunologic MechanismJanus Tyrosine KinasesCompound LibraryImmunotherapy	2015	87
Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability Anne‐Laure Grillot, Arnaud LeTiran, Dean Shannon, Journal of Medicinal Chemistry Metabolomic ProfilingReduced Metabolic LiabilityAntimicrobial ChemotherapyDrug ResistanceMedicinal Chemistry	2014	80
Studies Directed toward Asymmetric Synthesis of Cardioactive Steroids via Anionic Polycyclization Zhixiang Yang, Dean Shannon, Vouy-Linh Truong, Organic Letters	2002	36
Discovery of Novel, Orally Bioavailable β-Amino Acid Azaindole Inhibitors of Influenza PB2 Luc J. Farmer, Michael P. Clark, Michael J. Boyd, ACS Medicinal Chemistry Letters	2017	25
Discovery and Characterization of a Water-Soluble Prodrug of a Dual Inhibitor of Bacterial DNA Gyrase and Topoisomerase IV Hardwin O’Dowd, Dean Shannon, Kishan R. Chandupatla, ACS Medicinal Chemistry Letters Dual InhibitorPharmaceutical ScienceAntibiotic AdjuvantChemical BiologyLead Compound	2015	21

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