Arnaud LeTiran

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 222 citations · Full text

Bioorganic Chemistry, Antibacterial Activity, Molecular Biology +23

Quantitative Structure−Activity Relationship Analysis of Functionalized Amino Acid Anticonvulsant Agents Using <i>k</i> Nearest Neighbor and Simulated Annealing PLS Methods

Min Shen, Arnaud LeTiran, Yun-De Xiao et al. · Journal of Medicinal Chemistry · 2002 · 145 citations

Enantioselective Total Synthesis of Borrelidin

Matthew O. Duffey, Arnaud LeTiran, James P. Morken · Journal of the American Chemical Society · 2003 · 98 citations

Propionate Fragment, Natural Product Borrelidin, Biochemistry +9

Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability

Anne‐Laure Grillot, Arnaud LeTiran, Dean Shannon et al. · Journal of Medicinal Chemistry · 2014 · 80 citations · Full text

Metabolomic Profiling, Reduced Metabolic Liability, Antimicrobial Chemotherapy +19

Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues

Arnaud LeTiran, James P. Stables, Harold Kohn · Bioorganic & Medicinal Chemistry · 2001 · 70 citations

Medicine, Peptide Synthesis, Pharmacological Evaluation +5