Concepedia

Arnaud LeTiran

AL

Statistics

Publications

13

Citations

796

H-Index

11

Active since

2001

Affiliations

Vertex Pharmaceuticals (United States)(Current)

University of Houston

National Institutes of Health

National Institute of Neurological Disorders and Stroke

University of North Carolina at Chapel Hill

Arnaud LeTiran is an author at Vertex Pharmaceuticals (United States) specializing in medicinal chemistry, pharmacology, and pharmacy.

ORCID

Publications per year

2001–2021

13

Publications

13

Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity Relationships

Paul S. Charifson, Anne‐Laure Grillot, Trudy H. Grossman et al. · Journal of Medicinal Chemistry · 2008 · 225 citations · Full text

, , +16

Quantitative Structure−Activity Relationship Analysis of Functionalized Amino Acid Anticonvulsant Agents Using <i>k</i> Nearest Neighbor and Simulated Annealing PLS Methods

Min Shen, Arnaud LeTiran, Yun-De Xiao et al. · Journal of Medicinal Chemistry · 2002 · 145 citations

, , +15

Enantioselective Total Synthesis of Borrelidin

Matthew O. Duffey, Arnaud LeTiran, James P. Morken · Journal of the American Chemical Society · 2003 · 98 citations

, , +15

Second-Generation Antibacterial Benzimidazole Ureas: Discovery of a Preclinical Candidate with Reduced Metabolic Liability

Anne‐Laure Grillot, Arnaud LeTiran, Dean Shannon et al. · Journal of Medicinal Chemistry · 2014 · 82 citations · Full text

, , +16

Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues

Arnaud LeTiran, James P. Stables, Harold Kohn · Bioorganic & Medicinal Chemistry · 2001 · 70 citations

, , +12

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