Luc J. Farmer

Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

Michael P. Clark, Mark W. Ledeboer, Ioana Davies et al. · Journal of Medicinal Chemistry · 2014 · 211 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Synthesis and Biological Activity of a Novel Series of Nonsteroidal, Peripherally Selective Androgen Receptor Antagonists Derived from 1,2-Dihydropyridono[5,6-<i>g</i>]quinolines

Lawrence G. Hamann, Robert I. Higuchi, Lin Zhi et al. · Journal of Medicinal Chemistry · 1998 · 142 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases

Luc J. Farmer, Mark W. Ledeboer, Thomas Hoock et al. · Journal of Medicinal Chemistry · 2015 · 89 citations

Medicine, Medicinal Chemistry, Pharmacology +13

New nonsteroidal androgen receptor modulators based on 4-(trifluoromethyl)-2(1H)-pyrrolidino[3,2-g]quinolinone

James P. Edwards, Sarah J. West, Charlotte L. F. Pooley et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 78 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +12

Inhibitors of hepatitis C virus NS3·4A protease 2. Warhead SAR and optimization

Robert B. Perni, J. PITLIK, Shawn Britt et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacotherapy +12