Concepedia

Inhibitors of hepatitis C virus NS3·4A protease 2. Warhead SAR and optimization

Robert B. Perni, J. PITLIK, Shawn Britt, John J. Court, Lawrence F. Courtney, David D. Deininger, Luc J. Farmer, Cynthia A. Gates, Scott L. Harbeson, Rhonda B. Levin,

Bioorganic & Medicinal Chemistry Letters · 2004 · 63 citations · 21 references

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21

On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

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Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

Volker Lohmann, Frank Körner, Jan Oliver Koch et al. · Science · 1999 · 2.8K citations

, , +16

Kinetics of the reversible inhibition of enzyme-catalysed reactions by tight-binding inhibitors

John F. Morrison · Biochimica et Biophysica Acta (BBA) - Enzymology · 1969 · 814 citations

, , +16

Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere

Daniel P. Getman, Gary DeCrescenzo, R. Heintz et al. · Journal of Medicinal Chemistry · 1993 · 179 citations · Full text

, , +9

Expedient Method for the Solid-Phase Synthesis of Aspartic Acid Protease Inhibitors Directed toward the Generation of Libraries

Ellen K. Kick, Jonathan A. Ellman · Journal of Medicinal Chemistry · 1995 · 131 citations

, , +15