Lawrence F. Courtney

Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease

Robert B. Perni, Susan J. Almquist, Randal A. Byrn et al. · Antimicrobial Agents and Chemotherapy · 2006 · 382 citations · Full text

Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma

Bryce A. Harrison, N. Andrew Whitlock, Michael Voronkov et al. · Journal of Medicinal Chemistry · 2009 · 77 citations · Full text

Hypertension, Ocular Disease, Ophthalmology +14

Stereochemical analysis of the methyl transfer catalyzed by cobalamin-dependent methionine synthase from Escherichia coli B

Thomas M. Zydowsky, Lawrence F. Courtney, Verna Frasca et al. · Journal of the American Chemical Society · 1986 · 75 citations

Biosynthesis, Engineering, Biochemistry +12

Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Jeffrey T. Bagdanoff, Michael S. Donoviel, Amr Nouraldeen et al. · Journal of Medicinal Chemistry · 2009 · 74 citations · Full text

Immunology, Cell Death, Immunologic Mechanism +20

Inhibitors of hepatitis C virus NS3·4A protease 2. Warhead SAR and optimization

Robert B. Perni, J. PITLIK, Shawn Britt et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 62 citations · Full text

Immunology, Antiviral Drug Development, Hepatitis +9