Concepedia

The discovery and structure–activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymerase

Matthew G. LaPorte, Tandy L. Draper, Lori E. Miller, Charles W. Blackledge, Lara K. Leister, Eugene Amparo, Alison R. Hussey, Dorothy C. Young, Srinivas K. Chunduru, Christopher A. Benetatos,

Bioorganic & Medicinal Chemistry Letters · 2010 · 34 citations · 11 references

DOI

Concepts

References

11

The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994

Miriam J. Alter, Deanna Kruszon-Moran, Omana V. Nainan et al. · New England Journal of Medicine · 1999 · 3K citations · Full text

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National Institutes of Health Consensus Development Conference: Management of Hepatitis C: 2002

Leonard B. Seeff, Jay H. Hoofnagle · Hepatology · 2002 · 239 citations

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(Cyanomethylene)phosphoranes as Novel Carbonyl 1,1-Dipole Synthons: An Efficient Synthesis of .alpha.-Keto Acids, Esters, and Amides

Harry H. Wasserman, Wen‐Bin Ho · The Journal of Organic Chemistry · 1994 · 135 citations

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Discovery of (<i>R</i>)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-<i>a</i>]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor

Hui Li, John Tatlock, Angelica Linton et al. · Journal of Medicinal Chemistry · 2009 · 119 citations · Full text

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Discovery of Pyrano[3,4-<i>b</i>]indoles as Potent and Selective HCV NS5B Polymerase Inhibitors

Ariamala Gopalsamy, Kitae Lim, Gregory Ciszewski et al. · Journal of Medicinal Chemistry · 2004 · 97 citations · Full text

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