Srinivas K. Chunduru

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince, W. Wei‐Lynn Wong, Nufail Khan et al. · Cell · 2007 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

James E. Vince, Diep Chau, Bernard A. Callus et al. · The Journal of Cell Biology · 2008 · 235 citations · Full text

In vivo model of adeno-associated virus vector persistence and rescue

Sandra Afione, C. Conrad, W.G. Kearns et al. · Journal of Virology · 1996 · 224 citations · Full text

In Vivo Gene Therapy, Immunology, Viral Pathogenesis +16

Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models

Christopher A. Benetatos, Yasuhiro Mitsuuchi, Jennifer M. Burns et al. · Molecular Cancer Therapeutics · 2014 · 173 citations

Chemoprevention Strategy, Apoptosis, Immunology +22

Smac Mimetics Activate the E3 Ligase Activity of cIAP1 Protein by Promoting RING Domain Dimerization

Rebecca Feltham, Bodhi Bettjeman, Rhesa Budhidarmo et al. · Journal of Biological Chemistry · 2011 · 159 citations · Full text