Sandra Afione

Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

Terence R. Flotte, Sandra Afione, C. Conrad et al. · Proceedings of the National Academy of Sciences · 1993 · 487 citations

Adeno-associated Virus Vector, Viral Pathogenesis, Immunology +17

Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR

Marie E. Egan, Terence R. Flotte, Sandra Afione et al. · Nature · 1992 · 420 citations

Signal Transduction, Molecular Physiology, Signaling Pathway +13

Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter.

Terence R. Flotte, Sandra Afione, Rikki Solow et al. · Journal of Biological Chemistry · 1993 · 339 citations · Full text

Inflammatory Lung Disease, Molecular Regulation, Immunology +21

In vivo model of adeno-associated virus vector persistence and rescue

Sandra Afione, C. Conrad, W.G. Kearns et al. · Journal of Virology · 1996 · 224 citations · Full text

In Vivo Gene Therapy, Immunology, Viral Pathogenesis +16

Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration.

Terence R. Flotte, Sandra Afione, Pamela L. Zeitlin · American Journal of Respiratory Cell and Molecular Biology · 1994 · 223 citations

Active Cell Division, Viral Replication, Aav2 Vectors +13