Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

John R. Riordan, Johanna M. Rommens, Bat-Sheva Kerem et al. · Science · 1989 · 7.4K citations

Life Sciences, Genetics, Molecular Genetics +12

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson, Richard J. Gregory, Simon Thompson et al. · Science · 1991 · 1.1K citations

Natural Sciences, Cell Biology, Molecular Biology +17

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Devra P. Rich, Matthew P. Anderson, Richard J. Gregory et al. · Nature · 1990 · 706 citations

Life Sciences, Cell Biology, Molecular Biology +14

Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer

Mitchell L. Drumm, Heidi A. Pope, William Cliff et al. · Cell · 1990 · 578 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Nucleoside triphosphates are required to open the CFTR chloride channel

Matthew P. Anderson, Herbert A. Berger, Devra P. Rich et al. · Cell · 1991 · 525 citations

Natural Sciences, Cell Biology, Molecular Biology +13