Richard J. Gregory

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng, Richard J. Gregory, John Marshall et al. · Cell · 1990 · 1.8K citations

Fibrosis, Molecular Physiology, Defective Intracellular Transport +8

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson, Richard J. Gregory, Simon Thompson et al. · Science · 1991 · 1.1K citations

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Devra P. Rich, Matthew P. Anderson, Richard J. Gregory et al. · Nature · 1990 · 704 citations

Signal Transduction, Molecular Physiology, Membrane Transport +8

Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis

Joseph Zabner, Larry A. Couture, Richard J. Gregory et al. · Cell · 1993 · 677 citations

Gene Therapies, Chloride Transport Defect, Adenovirus-mediated Gene Transfer +4

Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

Seng H. Cheng, Devra P. Rich, John Marshall et al. · Cell · 1991 · 667 citations

R Domain, Signal Transduction, Molecular Physiology +11