James E. Vince

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince, W. Wei‐Lynn Wong, Nufail Khan et al. · Cell · 2007 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

Tobias L. Haas, Christoph H. Emmerich, Björn Gerlach et al. · Molecular Cell · 2009 · 753 citations · Full text

Transcriptional Regulation, Tnf-r1 Signaling Complex, Signal Transduction +10

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E. Lawlor, Nufail Khan, Alison Mildenhall et al. · Nature Communications · 2015 · 624 citations · Full text

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

James A. Rickard, Joanne A. O’Donnell, Joseph M. Evans et al. · Cell · 2014 · 576 citations · Full text

Inflammation, Cytokine, Receptor Tyrosine Kinase +7

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

Vitaliya Sagulenko, Sara J Thygesen, David P. Sester et al. · Cell Death and Differentiation · 2013 · 485 citations · Full text

Signal Transduction, Signaling Pathway, Pyroptotic Death Pathways +9