Nufail Khan

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

James E. Vince, W. Wei‐Lynn Wong, Nufail Khan et al. · Cell · 2007 · 1.1K citations · Full text

Signal Transduction, Signaling Pathway, Medicine +7

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Kate E. Lawlor, Nufail Khan, Alison Mildenhall et al. · Nature Communications · 2015 · 624 citations · Full text

Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

Stephen M. Condon, Yasuhiro Mitsuuchi, Yijun Deng et al. · Journal of Medicinal Chemistry · 2014 · 149 citations

Surgical Oncology, Solid Tumors, Apoptosis +20

In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8

Ian E. Gentle, W. Wei‐Lynn Wong, Joseph M. Evans et al. · Journal of Biological Chemistry · 2011 · 96 citations · Full text

Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways

Maria C. Tanzer, Nufail Khan, James Rickard et al. · Cell Death and Differentiation · 2017 · 56 citations · Full text

Inflammation, Molecular Immunology, Signal Transduction +10