RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

TL;DR

"The study investigates whether RIPK3 can promote inflammation independently of MLKL-mediated necroptosis." Findings: Summarize all findings: LPS triggers RIPK3 to activate caspase-8 and NLRP3–caspase-1 independent of RIPK3 kinase activity and MLKL when IAPs absent; in absence of IAPs and caspase-8, RIPK3 kinase activity and MLKL needed for TLR-induced NLRP3 activation; IL-1 dependent arthritis worsened in IAP-deficient mice, reduced by RIPK3 deletion but not MLKL; overall RIPK3 promotes NLRP3 inflammasome and IL-1β responses independent of MLKL and necroptotic cell death. Let's craft: "In IAP-deficient cells, LPS activates RIPK3 to trigger caspase‑8–mediated apoptosis and NLRP3–caspase‑1 inflammasome activation without requiring RIPK3 kinase activity or MLKL, whereas when both IAPs and caspase‑8 are absent, RIPK3 kinase activity and MLKL become essential for TLR‑induced NLRP3 activation; in vivo, IL‑1–dependent arthritis is exacerbated by loss of IAPs and mitigated by RIPK3 deletion but not MLKL, demonstrating that RIPK3 can drive NLRP3 inflammasome and IL‑1β responses independently of MLKL and necroptotic cell death." Check length: It's long but still one sentence. Ensure no semicolons?