Zhenyu Cai

Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis

Zhenyu Cai, Siriporn Jitkaew, Jie Zhao et al. · Nature Cell Biology · 2013 · 1.3K citations · Full text

Protein Function, Signal Transduction, Apoptosis +10

Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

Kewen Hu, Kun Li, Jing Lv et al. · Journal of Clinical Investigation · 2019 · 373 citations · Full text

Chemoprevention Strategy, Synthetic Lethality, Cancer Biology +16

Stem Cell Factor SOX2 Confers Ferroptosis Resistance in Lung Cancer via Upregulation of SLC7A11

Xinbo Wang, Yueqing Chen, Xudong Wang et al. · Cancer Research · 2021 · 263 citations · Full text

ZBP1 not RIPK1 mediates tumor necroptosis in breast cancer

Jin Young Baik, Zhaoshan Liu, Delong Jiao et al. · Nature Communications · 2021 · 162 citations · Full text

Activation of cell-surface proteases promotes necroptosis, inflammation and cell migration

Zhenyu Cai, Anling Zhang, Swati Choksi et al. · Cell Research · 2016 · 104 citations · Full text

Protease Inhibitors, Inflammation, Medicine +14