Joanne M. Hildebrand

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Publications

Citations

4.3K

H-Index

Active since

2010

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

Monash University

University of Iowa

The Royal Melbourne Hospital

Joanne M. Hildebrand is an author at Walter and Eliza Hall Institute of Medical Research specializing in life sciences, signal transduction, and cell death.

ORCID

Publications per year

2010–2024

Publications

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al. · Proceedings of the National Academy of Sciences · 2014 · 596 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

André L. Samson, Ying Zhang, Niall D. Geoghegan et al. · Nature Communications · 2020 · 358 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis

Emma J. Petrie, Jarrod J. Sandow, Annette V. Jacobsen et al. · Nature Communications · 2018 · 193 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Jaclyn S. Pearson, Cristina Giogha, Sabrina Mühlen et al. · Nature Microbiology · 2017 · 183 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

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