James M. Murphy

Statistics

Publications

254

Citations

21.3K

H-Index

Active since

1952

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

Indiana University – Purdue University Indianapolis

Indiana University School of Medicine

University of Indianapolis

James M. Murphy is an author at Walter and Eliza Hall Institute of Medical Research specializing in life sciences, molecular biology, and neuroscience.

ORCID

Publications per year

1952–2024

254

Publications

254

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al. · Proceedings of the National Academy of Sciences · 2014 · 596 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

James A. Rickard, Joanne A. O’Donnell, Joseph M. Evans et al. · Cell · 2014 · 587 citations · Full text

Life Sciences, Cell Biology, Immunology +11

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo et al. · Proceedings of the National Academy of Sciences · 2017 · 478 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

The molecular basis of JAK/STAT inhibition by SOCS1

Nicholas P. D. Liau, Artem Laktyushin, Isabelle S. Lucet et al. · Nature Communications · 2018 · 456 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

1–5 of 254