Stephanie A. Conos

A circRNA from SEPALLATA3 regulates splicing of its cognate mRNA through R-loop formation

Vanessa M. Conn, Véronique Hugouvieux, Aditya Nayak et al. · Nature Plants · 2017 · 594 citations

Transcriptional Regulation, Engineering, Genetics +11

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo et al. · Proceedings of the National Academy of Sciences · 2017 · 466 citations · Full text

Apoptosis, Immunology, Immune Regulation +26

HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death

Annette V. Jacobsen, Kym N. Lowes, Maria C. Tanzer et al. · Cell Death and Disease · 2016 · 153 citations · Full text

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation

Kate E. Lawlor, Rebecca Feltham, Monica Yabal et al. · Cell Reports · 2017 · 133 citations · Full text

Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway

Daniel S. Simpson, Jiyi Pang, Ashley Weir et al. · Immunity · 2022 · 129 citations · Full text

Inflammation, Cytokine, Interferon-γ Primes Macrophages +11