Concepedia

Isabelle S. Lucet

IS

Statistics

Publications

50

Citations

6.3K

H-Index

32

Active since

1999

Affiliations

The University of Melbourne(Current)

Walter and Eliza Hall Institute of Medical Research

Monash University

University of Oxford

University of Canterbury

Isabelle S. Lucet is an author at The University of Melbourne specializing in medicine, cell signaling, and signal transduction.

Top concepts

MedicineCell BiologyCell SignalingNatural SciencesSignal TransductionMolecular BiologyImmunologyBiochemistryCellular BiochemistryCell Death

Publications per year

1999–2023

50

Publications

50

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy, Peter E. Czabotar, Joanne M. Hildebrand et al. · Immunity · 2013 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +14

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Joanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet et al. · Proceedings of the National Academy of Sciences · 2014 · 581 citations · Full text

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio et al. · PLoS Pathogens · 2016 · 441 citations · Full text

Drug Target, Bioorganic Chemistry, Antiparasitic Agent +17

The molecular basis of JAK/STAT inhibition by SOCS1

Nicholas P. D. Liau, Artem Laktyushin, Isabelle S. Lucet et al. · Nature Communications · 2018 · 440 citations · Full text

A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties

James M. Murphy, Qingwei Zhang, Samuel N. Young et al. · Biochemical Journal · 2013 · 280 citations · Full text

Engineering, Molecular Biology, Biological Computing +25

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