James Rickard

Linear ubiquitination prevents inflammation and regulates immune signalling

Björn Gerlach, Stefanie M. Cordier, Anna C. Schmukle et al. · Nature · 2011 · 912 citations

Inflammation, Immunology, Immune Regulation +5

TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice

James Rickard, Holly Anderton, Nima Etemadi et al. · eLife · 2014 · 261 citations · Full text

Apoptosis, Immunology, Immune Regulation +16

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

Nieves Peltzer, Maurice Darding, Antonella Montinaro et al. · Nature · 2018 · 207 citations

Developmental Biology, Cell Division, Cell Death +5

In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8

Ian E. Gentle, W. Wei‐Lynn Wong, Joseph M. Evans et al. · Journal of Biological Chemistry · 2011 · 96 citations · Full text

TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1

Nima Etemadi, Michaël Chopin, Holly Anderton et al. · eLife · 2015 · 96 citations · Full text

Adaptive Immune System, Immunology, Immune Regulation +25