Angelica Linton

Discovery of (<i>R</i>)-6-Cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-<i>a</i>]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a Potent and Orally Available Hepatitis C Virus Polymerase Inhibitor

Hui Li, John Tatlock, Angelica Linton et al. · Journal of Medicinal Chemistry · 2009 · 118 citations · Full text

Viral Polymerase Structure, Pharmacotherapy, Antiviral Drug +16

Systematic Structure Modifications of Imidazo[1,2-<i>a</i>]pyrimidine to Reduce Metabolism Mediated by Aldehyde Oxidase (AO)

Angelica Linton, Ping Kang, Martha A. Ornelas et al. · Journal of Medicinal Chemistry · 2011 · 80 citations

Androgen Receptor, Bioorganic Chemistry, Molecular Biology +22

Preclinical Characterization of PF-00868554, a Potent Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Stephanie T. Shi, Koleen J. Herlihy, Joanne P. Graham et al. · Antimicrobial Agents and Chemotherapy · 2009 · 75 citations · Full text

Genotype 1A, Immunology, Molecular Biology +18

Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists

Chuangxing Guo, Angelica Linton, Susan E. Kephart et al. · Journal of Medicinal Chemistry · 2011 · 67 citations · Full text

Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors

Hui Li, John Tatlock, Angelica Linton et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 54 citations · Full text

Biochemistry, Natural Sciences, Novel Dihydropyrones +8