Concepedia

Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates

Kenneth J. Rodgers, Roger T. Dean

The International Journal of Biochemistry & Cell Biology · 2003 · 96 citations · 32 references

DOI

Concepts

References

32

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

, , +14

Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin

Gabriel Fenteany, Robert F. Standaert, William S. Lane et al. · Science · 1995 · 1.6K citations

, , +15

Epoxomicin, a potent and selective proteasome inhibitor, exhibits <i>in vivo</i> antiinflammatory activity

Lihao Meng, Royce Mohan, Benjamin H. Kwok et al. · Proceedings of the National Academy of Sciences · 1999 · 933 citations

, , +15

Proteasomal function is impaired in substantia nigra in Parkinson's disease

Kevin St. P. McNaught, Peter Jenner · Neuroscience Letters · 2001 · 648 citations

, , +14

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

Maria Gaczyńska, Kenneth L. Rock, Alfred L. Goldberg · Nature · 1993 · 572 citations

, , +11