γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.

Lynda A. Morrison, Aron E. Lukacher, V L Braciale et al. · The Journal of Experimental Medicine · 1986 · 509 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Proteinase yscE, the yeast proteasome/multicatalytic‐multifunctional proteinase: mutants unravel its function in stress induced proteolysis and uncover its necessity for cell survival.

Wolfgang Heinemeyer, J. A. Kleinschmidt, Jürgen Saidowsky et al. · The EMBO Journal · 1991 · 420 citations

Life Sciences, Biochemistry, Molecular Biology +15

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

Thomas A. Spies, Robert DeMars · Nature · 1991 · 416 citations

Life Sciences, Immunology, Molecular Biology +11

Second proteasome-related gene in the human MHC class II region

Adrian Kelly, Stephen H. Powis, Richard Glynne et al. · Nature · 1991 · 345 citations

Life Sciences, Genetics, Molecular Biology +9

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

Alain Townsend, J Bastin, Keith G. Gould et al. · The Journal of Experimental Medicine · 1988 · 331 citations · Full text

Life Sciences, Immunology, Infectious Diseases +16